期刊
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
卷 44, 期 6, 页码 623-627出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10863-012-9464-x
关键词
Cancer metastasis; Mitochondria; Glycolysis; ROS; Apoptosis
资金
- National Research Foundation of Korea [1201000350]
Mitochondria, also known as Power House of cell, are crucial organelles, regulating energy metabolism. Recently, an involvement of mitochondria in cancer occurrence and metastasis has been proposed. The roles of mitochondria in cancer progression/metastasis include alteration of glycolysis, regulation of ROS and suppression of intrinsic apoptosis. This mini-review explains the specific mitochondrial characteristics during cancer metastasis with past and recent findings. It may contribute to understanding mitochondria-related mechanisms of cancer metastasis.
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