相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A Randomized, Double-Blind Phase 2 Clinical Trial of Blosozumab, a Sclerostin Antibody, in Postmenopausal Women with Low Bone Mineral Density
Robert R. Recker et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2015)
Osteogenesis imperfecta: Clinical diagnosis, nomenclature and severity assessment
F. S. Van Dijk et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2014)
Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus
Ling Oei et al.
BONE (2014)
Antioxidants and human diseases
Peramaiyan Rajendran et al.
CLINICA CHIMICA ACTA (2014)
Epigenetic mechanisms in bone
Peter Vrtacnik et al.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2014)
Wnt and the Wnt signaling pathway in bone development and disease
Yiping Wang et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2014)
Multistage genome-wide association meta-analyses identified two new loci for bone mineral density
Lei Zhang et al.
HUMAN MOLECULAR GENETICS (2014)
Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium
Alireza Moayyeri et al.
HUMAN MOLECULAR GENETICS (2014)
Dysapoptosis of Osteoblasts and Osteocytes Increases Cancellous Bone Formation But Exaggerates Cortical Porosity With Age
Robert L. Jilka et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
Osteoporosis Caused by Mutations in PLS3: Clinical and Bone Tissue Characteristics
Somayyeh Fahiminiya et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus
Ling Oei et al.
JOURNAL OF MEDICAL GENETICS (2014)
MicroRNAs and post-transcriptional regulation of skeletal development
Beatriz Gamez et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2014)
Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta
Ingo Grafel et al.
NATURE MEDICINE (2014)
Autophagy-a key player in cellular and body metabolism
Kook Hwan Kim et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
Romosozumab in Postmenopausal Women with Low Bone Mineral Density
Michael R. McClung et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
A brilliant breakthrough in OI type V
S. Lazarus et al.
OSTEOPOROSIS INTERNATIONAL (2014)
Next-generation sequencing: a frameshift in skeletal dysplasia gene discovery
S. Lazarus et al.
OSTEOPOROSIS INTERNATIONAL (2014)
Sclerosing Bone Dysplasias: Leads Toward Novel Osteoporosis Treatments
Igor Fijalkowski et al.
CURRENT OSTEOPOROSIS REPORTS (2014)
Biological Regulation of Bone Quality
Tamara Alliston
CURRENT OSTEOPOROSIS REPORTS (2014)
Mutations in WNT1 Cause Different Forms of Bone Fragility
Katharina Keupp et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Whole-exome sequencing reveals a heterozygous LRP5 mutation in a 6-year-old boy with vertebral compression fractures and low trabecular bone density
Somayyeh Fahiminiya et al.
BONE (2013)
For whom the bell tolls: Distress signals from long-lived osteocytes and the pathogenesis of metabolic bone diseases
Stavros C. Manolagas et al.
BONE (2013)
Nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney
Jean-Philippe Bonjour
BRITISH JOURNAL OF NUTRITION (2013)
Bone Collagen: New Clues to Its Mineralization Mechanism from Recessive Osteogenesis Imperfecta
David R. Eyre et al.
CALCIFIED TISSUE INTERNATIONAL (2013)
An eQTL mapping approach reveals that rare variants in the SEMA5A regulatory network impact autism risk
Ye Cheng et al.
HUMAN MOLECULAR GENETICS (2013)
Suppression of Autophagy in Osteocytes Mimics Skeletal Aging
Melda Onal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Suppression of Autophagy by FIP200 Deletion Leads to Osteopenia in Mice Through the Inhibition of Osteoblast Terminal Differentiation
Fei Liu et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2013)
New Genes in Bone Development: What's New in Osteogenesis Imperfecta
Joan C. Marini et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Dairy in Adulthood: From Foods to Nutrient Interactions on Bone and Skeletal Muscle Health
Jean-Philippe Bonjour et al.
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2013)
The role of estrogen and androgen receptors in bone health and disease
Stavros C. Manolagas et al.
NATURE REVIEWS ENDOCRINOLOGY (2013)
PLS3 Mutations in X-Linked Osteoporosis with Fractures
Fleur S. van Dijk et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
WNT1 Mutations in Early-Onset Osteoporosis and Osteogenesis Imperfecta
Christine M. Laine et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators
Andrew D. Redfern et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Fruit and vegetable intake and bone mass in Chinese adolescents, young and postmenopausal women
Jing-Jing Li et al.
PUBLIC HEALTH NUTRITION (2013)
The role of extracellular modulators of canonical Wnt signaling in bone metabolism and diseases
Eveline Boudin et al.
SEMINARS IN ARTHRITIS AND RHEUMATISM (2013)
Vitamin D and Bone Disease
S. Christodoulou et al.
BIOMED RESEARCH INTERNATIONAL (2013)
MicroRNA Functions in Osteogenesis and Dysfunctions in Osteoporosis
Andre J. van Wijnen et al.
CURRENT OSTEOPOROSIS REPORTS (2013)
Primary osteoporosis without features of OI in children and adolescents: Clinical and genetic characteristics
Christine M. Laine et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2012)
Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity
Johanna Korvala et al.
BMC MEDICAL GENETICS (2012)
Increased proportion of hypermineralized osteocyte lacunae in osteoporotic and osteoarthritic human trabecular bone: Implications for bone remodeling
Vincent T. Carpentier et al.
BONE (2012)
Bone turnover markers in peripheral blood and marrow plasma reflect trabecular bone loss but not endocortical expansion in aging mice
Mohammad Shahnazari et al.
BONE (2012)
Do Epigenetic Marks Govern Bone Mass and Homeostasis?
Jesus Delgado-Calle et al.
CURRENT GENOMICS (2012)
Role of DNA methylation in the regulation of the RANKL-OPG system in human bone
Jesus Delgado-Calle et al.
EPIGENETICS (2012)
EMQN best practice guidelines for the laboratory diagnosis of osteogenesis imperfecta
Fleur S. van Dijk et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2012)
Mutations in PLOD2 Cause Autosomal-Recessive Connective Tissue Disorders Within the Bruck Syndrome-Osteogenesis Imperfecta Phenotypic Spectrum
Maria Trinidad Puig-Hervas et al.
HUMAN MUTATION (2012)
Pro-survival Effects of 17β-Estradiol on Osteocytes Are Mediated by Nitric Oxide/cGMP via Differential Actions of cGMP-dependent Protein Kinases I and II
Nisha Marathe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
DNA Methylation Contributes to the Regulation of Sclerostin Expression in Human Osteocytes
Jesus Delgado-Calle et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2012)
Autophagy: A new player in skeletal maintenance?
Lynne J. Hocking et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2012)
Androgen Receptor (AR) in Osteocytes Is Important for the Maintenance of Male Skeletal Integrity: Evidence From Targeted AR Disruption in Mouse Osteocytes
Mieke Sinnesael et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2012)
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
Karol Estrada et al.
NATURE GENETICS (2012)
Osteoporosis, frailty and fracture: implications for case finding and therapy
Joop P. van den Bergh et al.
NATURE REVIEWS RHEUMATOLOGY (2012)
Fruits and dietary phytochemicals in bone protection
Chwan-Li Shen et al.
NUTRITION RESEARCH (2012)
Epigenetic influences in the developmental origins of osteoporosis
C. Holroyd et al.
OSTEOPOROSIS INTERNATIONAL (2012)
Extraskeletal benefits and risks of calcium, vitamin D and anti-osteoporosis medications
J. -J. Body et al.
OSTEOPOROSIS INTERNATIONAL (2012)
Osteoblastogenesis regulation signals in bone remodeling
C. Zuo et al.
OSTEOPOROSIS INTERNATIONAL (2012)
The effects of smoking on bone metabolism
V. Yoon et al.
OSTEOPOROSIS INTERNATIONAL (2012)
Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus
Carolina Medina-Gomez et al.
PLOS GENETICS (2012)
Effects of Bone Matrix Proteins on Fracture and Fragility in Osteoporosis
Grazyna E. Sroga et al.
CURRENT OSTEOPOROSIS REPORTS (2012)
Mutations in FKBP10 Cause Both Bruck Syndrome and Isolated Osteogenesis Imperfecta in Humans
Ranad Shaheen et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2011)
Nosology and Classification of Genetic Skeletal Disorders: 2010 Revision
Matthew L. Warman et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2011)
Unraveling the role of FoxOs in bone-Insights from mouse models
Maria Almeida
BONE (2011)
Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption
Carl J. DeSelm et al.
DEVELOPMENTAL CELL (2011)
Sirt1 Is a Regulator of Bone Mass and a Repressor of Sost Encoding for Sclerostin, a Bone Formation Inhibitor
Einav Cohen-Kfir et al.
ENDOCRINOLOGY (2011)
Cytoplasmic Superoxide Causes Bone Fragility Owing to Low-Turnover Osteoporosis and Impaired Collagen Cross-Linking
Hidetoshi Nojiri et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2011)
Central (ICV) Leptin Injection Increases Bone Formation, Bone Mineral Density, Muscle Mass, Serum IGF-1, and the Expression of Osteogenic Genes in Leptin-Deficient ob/ob Mice
Shoshana M. Bartell et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2011)
Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women
S. Chew et al.
OSTEOPOROSIS INTERNATIONAL (2011)
Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk
Emma L. Duncan et al.
PLOS GENETICS (2011)
Effects of Nutrition and Alcohol Consumption on Bone Loss
Martin J. J. Ronis et al.
Current Osteoporosis Reports (2011)
Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone
Bjoern Busse et al.
AGING CELL (2010)
Identification of a Frameshift Mutation in Osterix in a Patient with Recessive Osteogenesis Imperfecta
Pablo Lapunzina et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2010)
Various Types of LRP5 Mutations in Four Patients With Osteoporosis-Pseudoglioma Syndrome: Identification of a 7.2-kb Microdeletion Using Oligonucleotide Tiling Microarray
Satoshi Narumi et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2010)
Reactive oxygen species on bone mineral density and mechanics in Cu,Zn superoxide dismutase (Sod1) knockout mice
Michael J. Smietana et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
FoxO-Mediated Defense against Oxidative Stress in Osteloblasts, Is Indispensable for Skeletal Homeostasis in Mice
Elena Ambrogini et al.
CELL METABOLISM (2010)
Genetics of Osteoporosis
Stuart H. Ralston et al.
ENDOCRINE REVIEWS (2010)
From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis
Stavros C. Manolagas
ENDOCRINE REVIEWS (2010)
Perspectives: How many women have osteoporosis now?
Joseph L. Melton
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Pathway-Based Genome-Wide Association Analysis Identified the Importance of Regulation-of-Autophagy Pathway for Ultradistal Radius BMD
Lishu Zhang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Effects of Chronic Estrogen Treatment on Modulating Age-Related Bone Loss in Female Mice
Farhan A. Syed et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
A Role for Ethanol-Induced Oxidative Stress in Controlling Lineage Commitment of Mesenchymal Stromal Cells Through Inhibition of Wnt/β-Catenin Signaling
Jin-Ran Chen et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Genetic Determinants of Bone Density and Fracture Risk-State of the Art and Future Directions
Emma L. Duncan et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study
Roger M. D. Zebaze et al.
LANCET (2010)
The Estrogen Receptor-α in Osteoclasts Mediates the Protective Effects of Estrogens on Cancellous But Not Cortical Bone
Marta Martin-Millan et al.
MOLECULAR ENDOCRINOLOGY (2010)
Mechanical signals as anabolic agents in bone
Engin Ozcivici et al.
NATURE REVIEWS RHEUMATOLOGY (2010)
Genome-wide copy number variation association study suggested VPS13B gene for osteoporosis in Caucasians
F. -Y. Deng et al.
OSTEOPOROSIS INTERNATIONAL (2010)
Osteocyte: the unrecognized side of bone tissue
G. Y. Rochefort et al.
OSTEOPOROSIS INTERNATIONAL (2010)
European Bone Mineral Density Loci Are Also Associated with BMD in East-Asian Populations
Unnur Styrkarsdottir et al.
PLOS ONE (2010)
Nutrient-dependent regulation of autophagy through the target of rapamycin pathway
Yu-Yun Chang et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Mineralization and Bone Resorption Are Regulated by the Androgen Receptor in Male Mice
Cherie Chiang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
Fernando Rivadeneira et al.
NATURE GENETICS (2009)
Excess mortality following hip fracture: a systematic epidemiological review
B. Abrahamsen et al.
OSTEOPOROSIS INTERNATIONAL (2009)
Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
Colin Selman et al.
SCIENCE (2009)
Genome-wide Copy-Number-Variation Study Identified a Susceptibility Gene, UGT2B17, for Osteoporosis
Tie-Lin Yang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study
J. B. Richards et al.
LANCET (2008)
Multiple genetic loci for bone mineral density and fractures
Unnur Styrkarsdottir et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of transcription 3/receptor activator of nuclear factor-kappa B ligand signaling cascade
Jin-Ran Chen et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids
Maria Almeida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting β-catenin from T cell factor- to Forkhead box O-mediated transcription
Maria Almeida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Estrogen prevents bone loss via estrogen receptor α and induction of Fas ligand in osteoclasts
Takashi Nakamura et al.
CELL (2007)
Minireview:: The genetics of low-density lipoprotein Receptor-related protein 5 in bone:: A story of extremes
Wendy Balemans et al.
ENDOCRINOLOGY (2007)
Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice
Amanda J. Notini et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2007)
Impact of seafood and fruit consumption on bone mineral density
Pierre Zalloua et al.
MATURITAS (2007)
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling
XY Wang et al.
JOURNAL OF CELL BIOLOGY (2006)
Missense mutations in LRP5 are not a common cause of idiopathic osteoporosis in adult men
P Crabbe et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2005)
The decline of androgen levels in elderly men and its clinical and therapeutic implications
JM Kaufman et al.
ENDOCRINE REVIEWS (2005)
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
M Giorgio et al.
CELL (2005)
SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
M Semënov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Functional interaction between β-catenin and FOXO in oxidative stress signaling
MAG Essers et al.
SCIENCE (2005)
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
XF Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Requirements for DXA for the management of osteoporosis in Europe
JA Kanis et al.
OSTEOPOROSIS INTERNATIONAL (2005)
Smoking and fracture risk: a meta-analysis
JA Kanis et al.
OSTEOPOROSIS INTERNATIONAL (2005)
p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells
S Pacini et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Modulation of mammalian life span by the short isoform of p53
B Maier et al.
GENES & DEVELOPMENT (2004)
Reversal of bone loss in mice by nongenotropic signaling of sex steroids
S Kousteni et al.
SCIENCE (2002)
Pathogenesis of bone fragility in women and men
E Seeman
LANCET (2002)
Premature aging in mice deficient in DNA repair and transcription
J de Boer et al.
SCIENCE (2002)
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
S Nemoto et al.
SCIENCE (2002)
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
W Balemans et al.
JOURNAL OF MEDICAL GENETICS (2002)
p53 mutant mice that display early ageing-associated phenotypes
SD Tyner et al.
NATURE (2002)
Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women - Results from the National Osteoporosis Risk Assessment
ES Siris et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
YQ Gong et al.
CELL (2001)
Oxidative stress and antioxidants in exercise
C Leeuwenburgh et al.
CURRENT MEDICINAL CHEMISTRY (2001)
A meta-analysis of the effects of cigarette smoking on bone mineral density
KD Ward et al.
CALCIFIED TISSUE INTERNATIONAL (2001)
Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: Dissociation from transcriptional activity
S Kousteni et al.
CELL (2001)
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
W Balemans et al.
HUMAN MOLECULAR GENETICS (2001)
Acquisition of optimal bane mass in childhood and adolescence
LK Bachrach
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2001)
Increased cell surface expression of receptors for transforming growth factor-β on osteoblasts from patients with osteogenesis imperfecta
J Gebken et al.
PATHOBIOLOGY (2000)