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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
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PLOS ONE (2013)
The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush
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Selective tau tyrosine nitration in non-AD tauopathies
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BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
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EMBO REPORTS (2012)
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
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FASEB JOURNAL (2012)
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HUMAN MOLECULAR GENETICS (2012)
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Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability
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Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
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NEUROBIOLOGY OF AGING (2012)
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EMBO JOURNAL (2011)
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HUMAN MOLECULAR GENETICS (2011)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Neuropathology of Frontotemporal Lobar Degeneration-Tau (FTLD-Tau)
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JOURNAL OF NEUROSCIENCE (2011)
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
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In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
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HIPPOCAMPUS (2010)
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JOURNAL OF NEUROSCIENCE (2010)
Aβ Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
Hans Zempel et al.
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Alix de Calignon et al.
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Stephanie J. Adams et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
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Alberto Gomez-Ramos et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2009)
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Almudena Fuster-Matanzo et al.
FEBS LETTERS (2009)
SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans
Chris R. Guthrie et al.
HUMAN MOLECULAR GENETICS (2009)
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
Yipeng Wang et al.
HUMAN MOLECULAR GENETICS (2009)
Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Activated Actin-Depolymerizing Factor/Cofilin Sequesters Phosphorylated Microtubule-Associated Protein during the Assembly of Alzheimer-Like Neuritic Cytoskeletal Striations
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JOURNAL OF NEUROSCIENCE (2009)
Transmission and spreading of tauopathy in transgenic mouse brain
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NATURE CELL BIOLOGY (2009)
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
Diane P. Hanger et al.
TRENDS IN MOLECULAR MEDICINE (2009)
Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
Marco D. Mukrasch et al.
PLOS BIOLOGY (2009)
Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, Grb2, and Src family kinases
C. Hugh Reynolds et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
I1PP2A affects Tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A
She Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons
Tara L. Spires-Jones et al.
JOURNAL OF NEUROSCIENCE (2008)
The potential for β-structure in the repeat domain of Tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
Maria-Magdalena Mocanu et al.
JOURNAL OF NEUROSCIENCE (2008)
Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
Aidong Yuan et al.
JOURNAL OF NEUROSCIENCE (2008)
Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone
Mitul Sarkar et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
A. Gomez-Ramos et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Differential regulation of dynein and kinesin motor proteins by tau
Ram Dixit et al.
SCIENCE (2008)
Interaction of tau protein with the dynactin complex
Enrico Magnani et al.
EMBO JOURNAL (2007)
The β-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy
Katrin Eckermann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Swimming against the tide: Mobility of the microtubule-associated protein tau in neurons
Sven Konzack et al.
JOURNAL OF NEUROSCIENCE (2007)
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements
Ayodeji A. Asuni et al.
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SUT-1 enables tau-induced neurotoxicity in C-elegans
Brian C. Kraemer et al.
HUMAN MOLECULAR GENETICS (2007)
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
Y. P. Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
Erik D. Roberson et al.
SCIENCE (2007)
Granular tau oligomers as intermediates of tau filaments
Sumihiro Maeda et al.
BIOCHEMISTRY (2007)
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Emmanuel Planel et al.
JOURNAL OF NEUROSCIENCE (2007)
Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1
Edda Thies et al.
JOURNAL OF NEUROSCIENCE (2007)
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
Chad A. Dickey et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
Tudor A. Fulga et al.
NATURE CELL BIOLOGY (2007)
Multiple-motor based transport and its regulation by Tau
Michael Vershinin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A beta Oligomers - a decade of discovery
Dominic M. Walsh et al.
JOURNAL OF NEUROCHEMISTRY (2007)
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Shigeo Takamori et al.
CELL (2006)
Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo
Norbert Zilka et al.
FEBS LETTERS (2006)
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity
Alejandra Del C. Alonso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Tau protein binds to pericentromeric DNA:: a putative role for nuclear tau in nucleolar organization
Marcela K. Sjoberg et al.
JOURNAL OF CELL SCIENCE (2006)
Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage:: in vitro evidence and implications for tangle formation in vivo
AL Guillozet-Bongaarts et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and α-synuclein
V Dorval et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Global hairpin folding of tau in solution
S Jeganathan et al.
BIOCHEMISTRY (2006)
Rapamycin alleviates toxicity of different aggregate-prone proteins
Z Berger et al.
HUMAN MOLECULAR GENETICS (2006)
Inducible expression of tau repeat domain in cell models of tauopathy - Aggregation is toxic to cells but can be reversed by inhibitor drugs
I Khlistunova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Disease-related modifications in tau affect the interaction between Fyn and tau
K Bhaskar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Molecular motors implicated in the axonal transport of tau and α-synuclein
MA Utton et al.
JOURNAL OF CELL SCIENCE (2005)
Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates
IE Vega et al.
MOLECULAR BRAIN RESEARCH (2005)
Tau suppression in a neurodegenerative mouse model improves memory function
K SantaCruz et al.
SCIENCE (2005)
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
JR Babu et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
C Andorfer et al.
JOURNAL OF NEUROSCIENCE (2005)
Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death
SC Feinstein et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
L Petrucelli et al.
HUMAN MOLECULAR GENETICS (2004)
Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: Implications for Alzheimer's disease
E Planel et al.
JOURNAL OF NEUROSCIENCE (2004)
Zeta 14-3-3 protein favours the formation of human tau fibrillar polymers
F Hernández et al.
NEUROSCIENCE LETTERS (2004)
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival
H Shimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Molecular aging of tau:: disulfide-independent aggregation and non-enzymatic degradation in vitro and in vivo
A Watanabe et al.
JOURNAL OF NEUROCHEMISTRY (2004)
O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
F Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Expression of tau mRNA and soluble tau isoforms in affected and non-affected brain areas in Alzheimer's disease
A Boutajangout et al.
FEBS LETTERS (2004)
Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis
E Sontag et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Triple-transgenic model of Alzheimer's disease with plaques and tangles:: Intracellular Aβ and synaptic dysfunction
S Oddo et al.
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Isoforms changes of tau protein during development in various species
H Takuma et al.
DEVELOPMENTAL BRAIN RESEARCH (2003)
SUMO-1 marks the nuclear inclusions in familial neuronal intranuclear inclusion disease
DL Pountney et al.
EXPERIMENTAL NEUROLOGY (2003)
Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity
J Biernat et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
K Stamer et al.
JOURNAL OF CELL BIOLOGY (2002)
Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5
F Liu et al.
NEUROSCIENCE (2002)
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
AD Alonso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Neurodegenerative tauopathies
VMY Lee et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)
Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias
S Barghorn et al.
BIOCHEMISTRY (2000)
Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure
M von Bergen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)