4.4 Article

Complete Genome Sequence of Desulfurococcus fermentans, a Hyperthermophilic Cellulolytic Crenarchaeon Isolated from a Freshwater Hot Spring in Kamchatka, Russia

期刊

JOURNAL OF BACTERIOLOGY
卷 194, 期 20, 页码 5703-5704

出版社

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01314-12

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资金

  1. Community Sequencing Program (CSP) of the U.S. Department of Energy's Joint Genome Institute (DOE-JGI)
  2. Office of Science of the U.S. Department of Energy [DE-AC02-05CH11231]
  3. NASA Astrobiology: Exobiology and Evolutionary Biology [NNG05GP24G, NNX09AV28G]
  4. National Science Foundation [MCB 1020458]
  5. Virginia Tech Genetics, Bioinformatics and Computational Biology Ph.D. program
  6. program of the Russian Academy of Sciences Molecular and Cell Biology
  7. American Society for Microbiology
  8. Fulbright Scholar award
  9. Direct For Biological Sciences
  10. Div Of Molecular and Cellular Bioscience [1020458] Funding Source: National Science Foundation
  11. NASA [105838, NNX09AV28G] Funding Source: Federal RePORTER

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Desulfurococcus fermentans is the first known cellulolytic archaeon. This hyperthermophilic and strictly anaerobic crenarchaeon produces hydrogen from fermentation of various carbohydrates and peptides without inhibition by accumulating hydrogen. The complete genome sequence reported here suggested that D. fermentans employs membrane-bound hydrogenases and novel glycohydrolases for hydrogen production from cellulose.

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