期刊
JOURNAL OF BACTERIOLOGY
卷 193, 期 17, 页码 4380-4387出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.05028-11
关键词
-
类别
资金
- Netherlands Proteomics Centre (NPC)
- Netherlands Science Organization (NWO)
- Max Planck Society
Crenarchaea, such as Sulfolobus acidocaldarius and Sulfolobus tokodaii, produce antimicrobial proteins called sulfolobicins. These antimicrobial proteins inhibit the growth of closely related species. Here we report the identification of the sulfolobicin-encoding genes in S. acidocaldarius. The active sulfolobicin comprises two proteins that are equipped with a classical signal sequence. These proteins are secreted by the cells and found to be membrane vesicle associated. Gene inactivation studies demonstrate that both proteins are required for the bacteriostatic antimicrobial activity. Sulfolobicins constitute a novel class of antimicrobial proteins without detectable homology to any other protein.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据