期刊
JOURNAL OF BACTERIOLOGY
卷 193, 期 5, 页码 1267-1272出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01276-10
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资金
- CEU [LSHM-CT-2006-019064, LSHG-CT-2006-037469]
- transnational SysMO initiative through BACELL SysMO
- Top Institute Pharma [T4-213]
The important human pathogen Staphylococcus aureus is known to spread on soft agar plates. Here, we show that colony spreading of S. aureus involves the agr quorum-sensing system. This finding can be related to the agr-dependent expression of biosurfactants, such as phenol-soluble modulins, suggesting a connection between spreading motility and virulence.
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