期刊
JOURNAL OF BACTERIOLOGY
卷 192, 期 22, 页码 5906-5913出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00777-10
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资金
- Research Council of Norway
Class IIa bacteriocins target a phylogenetically defined subgroup of mannose-phosphotransferase systems (man-PTS) on sensitive cells. By the use of man-PTS genes of the sensitive Listeria monocytogenes (mpt) and the nonsensitive Lactococcus lactis (ptn) species to rationally design a series of man-PTS chimeras and site-directed mutations, we identified an extracellular loop of the membrane-located protein MptC that was responsible for specific target recognition by the class IIa bacteriocins.
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