期刊
JOURNAL OF BACTERIOLOGY
卷 192, 期 18, 页码 4592-4596出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00448-10
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- Tel-Aviv University
- Israel Academy of Sciences and Humanities
The highly conserved bacterial ybeY gene is a heat shock gene whose function is not fully understood. Previously, we showed that the YbeY protein is involved in protein synthesis, as Escherichia coli mutants with ybeY deleted exhibit severe translational defects in vivo. Here we show that the in vitro activity of the translation machinery of ybeY deletion mutants is significantly lower than that of the wild type. We also show that the lower efficiency of the translation machinery is due to impaired 30S small ribosomal subunits.
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