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EUROPEAN JOURNAL OF HUMAN GENETICS (2007)
Association of polymorphisms across the tyrosine kinase gene, TYK2 in UKSLE families
D. S. C. Graham et al.
RHEUMATOLOGY (2007)
FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity
Manuela Fanciulli et al.
NATURE GENETICS (2007)
Involvement of renal tubular toll-like receptor 9 in the development of tubulointerstitial injury in systemic lupus
Ariela Benigni et al.
ARTHRITIS AND RHEUMATISM (2007)
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
Robert R. Graham et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Fc receptor genes and the systemic lupus erythematosus diathesis
Elizabeth E. Brown et al.
AUTOIMMUNITY (2007)
Mesangial cells of lupus-prone mice are sensitive to chemokine production
Shuk-Man Ka et al.
ARTHRITIS RESEARCH & THERAPY (2007)
FcR-bearing myeloid cells are responsible for triggering murine lupus nephritis
Amy Bergtold et al.
JOURNAL OF IMMUNOLOGY (2006)
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice
Prashant S. Patole et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2006)
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
Sean R. Christensen et al.
IMMUNITY (2006)
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
RR Graham et al.
NATURE GENETICS (2006)
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
T Vang et al.
NATURE GENETICS (2005)
RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling
JJ Coughlin et al.
JOURNAL OF IMMUNOLOGY (2005)
Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells
U Kunter et al.
KIDNEY INTERNATIONAL (2005)
Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts
RA Floto et al.
NATURE MEDICINE (2005)
Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells
Y Zheng et al.
BLOOD (2005)
STAT4 - A critical regulator of inflammation in vivo
MH Kaplan
IMMUNOLOGIC RESEARCH (2005)
Ets-1 deficiency leads to altered B cell differentiation, hyperresponsiveness to TLR9 and autoimmune disease
D Wang et al.
INTERNATIONAL IMMUNOLOGY (2005)
New approaches to the renal pathogenicity of anti-DNA antibodies in systemic lupus erythematosus
C Putterman
AUTOIMMUNITY REVIEWS (2004)
A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters
DM Roberts et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients
HD Shin et al.
HUMAN MOLECULAR GENETICS (2004)
Induction of B7-1 in podocytes is associated with nephrotic syndrome
J Reiser et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Pivotal role of Stat4 and Stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice
CO Jacob et al.
JOURNAL OF IMMUNOLOGY (2003)
Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus
AM Jacobi et al.
ARTHRITIS AND RHEUMATISM (2003)
The FcγRIIIA-F158 allele is a risk factor for the development of lupus nephritis:: A meta-analysis
FB Karassa et al.
KIDNEY INTERNATIONAL (2003)
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase
PL Cohen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
EA Leadbetter et al.
NATURE (2002)
Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn
CCK Yu et al.
CURRENT BIOLOGY (2001)
Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains
L Morel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation
DM Frucht et al.
JOURNAL OF IMMUNOLOGY (2000)