期刊
NATURE REVIEWS MICROBIOLOGY
卷 13, 期 4, 页码 241-248出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro3398
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资金
- UK Biotechnology and Biological Sciences Research Council [BB/G015902/1]
- BBSRC [BB/G015902/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/G015902/1] Funding Source: researchfish
Work over the past decade has highlighted the pivotal role of the actin-like MreB family of proteins in the determination and maintenance of rod cell shape in bacteria. Early images of MreB localization revealed long helical filaments, which were suggestive of a direct role in governing cell wall architecture. However, several more recent, higher-resolution studies have questioned the existence or importance of the helical structures. In this Opinion article, I navigate a path through these conflicting reports, revive the helix model and summarize the key questions that remain to be answered.
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