4.6 Review

Physiological and pathophysiological roles of NAMPT and NAD metabolism

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells

Susanne Schuster et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Article Chemistry, Medicinal

NAD Biosynthesis in Humans - Enzymes, Metabolites and Therapeutic Aspects

Christian Dölle et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Increasing NAD Synthesis in Muscle via Nicotinamide Phosphoribosyltransferase Is Not Sufficient to Promote Oxidative Metabolism

David W. Frederick et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Medicine, Research & Experimental

Blockade of visfatin induction by oleanolic acid via disturbing IL-6-TRAF6-NF-κB signaling of adipocytes

Hyun-Sung Kim et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2014)

Article Endocrinology & Metabolism

Extracellular Visfatin Activates Gluconeogenesis in HepG2 Cells Through the Classical PKA/CREB-Dependent Pathway

Y. J. Choi et al.

HORMONE AND METABOLIC RESEARCH (2014)

Letter Cardiac & Cardiovascular Systems

Visfatin/Nampt induces telomere damage and senescence in human endothelial cells

Laura A. Villalobos et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2014)

Article Endocrinology & Metabolism

Neuronal NAMPT is released after cerebral ischemia and protects against white matter injury

Zheng Jing et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2014)

Article Biochemistry & Molecular Biology

Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes

Soo Jin Yang et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2014)

Article Geriatrics & Gerontology

Nicotinamide Phosphoribosyltransferase Is Required for the Calorie Restriction-Mediated Improvements in Oxidative Stress, Mitochondrial Biogenesis, and Metabolic Adaptation

Jie Song et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)

Article Endocrinology & Metabolism

Relationship between circulating visfatin/NAMPT, nutritional status and insulin resistance in an elderly population - results from the PolSenior substudy

Magdalena Olszanecka-Glinianowicz et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2014)

Article Multidisciplinary Sciences

Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues

Valerio Mori et al.

PLOS ONE (2014)

Review Cell Biology

NAD+ and sirtuins in aging and disease

Shin-ichiro Imai et al.

TRENDS IN CELL BIOLOGY (2014)

Review Endocrinology & Metabolism

SIRT1 and other sirtuins in metabolism

Hung-Chun Chang et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)

Review Endocrinology & Metabolism

Adipokines - removing road blocks to obesity and diabetes therapy

Matthias Blueher

MOLECULAR METABOLISM (2014)

Review Endocrinology & Metabolism

Mechanism linking diabetes mellitus and obesity

Abdullah S. Al-Goblan et al.

DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2014)

Article Cardiac & Cardiovascular Systems

Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling

Vinodkumar B. Pillai et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)

Article Medicine, Research & Experimental

Association of adipokines with obesity in children and adolescents

Anila Jaleel et al.

BIOMARKERS IN MEDICINE (2013)

Article Medical Laboratory Technology

Plasma visfatin levels and gene expression in morbidly obese women with associated fatty liver disease

Teresa Auguet et al.

CLINICAL BIOCHEMISTRY (2013)

Review Biochemistry & Molecular Biology

NAD+ metabolism: A therapeutic target for age-related metabolic disease

Laurent Mouchiroud et al.

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2013)

Review Biochemistry & Molecular Biology

A role of intracellular mono-ADP-ribosylation in cancer biology

Emanuele S. Scarpa et al.

FEBS JOURNAL (2013)

Article Obstetrics & Gynecology

Seminal plasma adipokine levels are correlated with functional characteristics of spermatozoa

Stephanie Thomas et al.

FERTILITY AND STERILITY (2013)

Article Oncology

Visfatin, a potential biomarker and prognostic factor for endometrial cancer

Wenyan Tian et al.

GYNECOLOGIC ONCOLOGY (2013)

Article Oncology

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells

Basant Kumar Thakur et al.

INTERNATIONAL JOURNAL OF CANCER (2013)

Article Biochemistry & Molecular Biology

CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells

Alessia Grozio et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Chemistry, Medicinal

Nicotinamide Phosphoribosyltransferase Inhibitors, Design, Preparation, and Structure-Activity Relationship

Mette K. Christensen et al.

JOURNAL OF MEDICINAL CHEMISTRY (2013)

Article Chemistry, Medicinal

Medicinal Chemistry of Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors

Ubaldina Galli et al.

JOURNAL OF MEDICINAL CHEMISTRY (2013)

Article Chemistry, Multidisciplinary

Recycling Nicotinamide. The Transition-State Structure of Human Nicotinamide Phosphoribosyltransferase

Emmanuel S. Burgos et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Review Biochemistry & Molecular Biology

Poly(ADP-ribose): PARadigms and PARadoxes

Alexander Buerkle et al.

MOLECULAR ASPECTS OF MEDICINE (2013)

Review Cell Biology

Visfatin/Nampt: An Adipokine with Cardiovascular Impact

Tania Romacho et al.

MEDIATORS OF INFLAMMATION (2013)

Article Endocrinology & Metabolism

Effect of Weight Reduction Following Bariatric Surgery on Serum Visfatin and Adiponectin Levels in Morbidly Obese Subjects

Mohammad Javad Hosseinzadeh-Attar et al.

OBESITY FACTS (2013)

Article Multidisciplinary Sciences

Expression and Regulation of Nampt in Human Islets

Karen Kover et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Ox-LDL Induces ER Stress and Promotes the adipokines Secretion in 3T3-L1 Adipocytes

Yaqin Chen et al.

PLOS ONE (2013)

Review Gastroenterology & Hepatology

What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome?

Giovanni Tarantino et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2013)

Article Cell Biology

Age-related cognitive decline: Can neural stem cells help us?

Benedetta Artegiani et al.

AGING-US (2012)

Article Endocrinology & Metabolism

Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice

Hongliang Li et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)

Article Endocrinology & Metabolism

Diurnal Rhythm of Circulating Nicotinamide Phosphoribosyltransferase (Nampt/Visfatin/PBEF): Impact of Sleep Loss and Relation to Glucose Metabolism

Christian Benedict et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Article Endocrinology & Metabolism

Adipocytes as a Source of Increased Circulating Levels of Nicotinamide Phosphoribosyltransferase/Visfatin in Active Acromegaly

Nicoleta C. Olarescu et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Article Medical Laboratory Technology

Visfatin Levels in Nonalcoholic Fatty Liver Disease

Erdem Akbal et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2012)

Article Multidisciplinary Sciences

Circadian Desynchrony Promotes Metabolic Disruption in a Mouse Model of Shiftwork

Johanna L. Barclay et al.

PLOS ONE (2012)

Article Endocrinology & Metabolism

Serum Visfatin Levels, Adiposity and Glucose Metabolism in Obese Adolescents

Derya Taskesen et al.

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY (2012)

Review Oncology

The NAD metabolome - a key determinant of cancer cell biology

Alberto Chiarugi et al.

NATURE REVIEWS CANCER (2012)

Article Medicine, General & Internal

Visfatin in juvenile obesity - the effect of obesity intervention and sex

Malgorzata Krzystek-Korpacka et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Biochemistry & Molecular Biology

Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene

Rongya Tao et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Endocrinology & Metabolism

Involvement of visfatin in palmitate-induced upregulation of inflammatory cytokines in hepatocytes

Yong Jun Choi et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2011)

Article Endocrinology & Metabolism

Vaspin and visfatin/Nampt are interesting interrelated adipokines playing a role in the pathogenesis of type 2 diabetes mellitus

Hala O. El-Mesallamy et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2011)

Article Neurosciences

Visfatin induces neurite outgrowth in PC12 cells via ERK1/2 signaling pathway

Young-Soon Kang et al.

NEUROSCIENCE LETTERS (2011)

Article Endocrinology & Metabolism

Skeletal muscle NAMPT is induced by exercise in humans

Sheila R. Costford et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)

Article Biochemistry & Molecular Biology

Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes

A. Garten et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Article Pharmacology & Pharmacy

Pre-B Cell Colony Enhancing Factor/NAMPT/Visfatin in Inflammation and Obesity- Related Disorders

Alexander R. Moschen et al.

CURRENT PHARMACEUTICAL DESIGN (2010)

Article Biochemistry & Molecular Biology

Genetic variation in the visfatin (PBEF1/NAMPT) gene and type 2 diabetes in the Greek population

Peristera Paschou et al.

CYTOKINE (2010)

Article Biochemistry & Molecular Biology

Body fat distribution has no effect on serum visfatin levels in healthy female subjects

Canan Ersoy et al.

CYTOKINE (2010)

Article Agriculture, Dairy & Animal Science

Visfatin regulates genes related to lipid metabolism in porcine adipocytes

C. C. Yang et al.

JOURNAL OF ANIMAL SCIENCE (2010)

Article Biochemistry & Molecular Biology

Inhibition of Nicotinamide Phosphoribosyltransferase CELLULAR BIOENERGETICS REVEALS A MITOCHONDRIAL INSENSITIVE NAD POOL

Maria Pittelli et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Medicine, Research & Experimental

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice

Carlos Escande et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Cell Biology

Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats

Erika Koltai et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2010)

Article Biochemistry & Molecular Biology

Upregulation of fibroblast growth factor-2 by visfatin that promotes endothelial angiogenesis

Yun-Hee Bae et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Article Pharmacology & Pharmacy

Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo

Laura Formentini et al.

BIOCHEMICAL PHARMACOLOGY (2009)

Article Endocrinology & Metabolism

Relationship Between Cerebrospinal Fluid Visfatin (PBEF/Nampt) Levels and Adiposity in Humans

Manfred Hallschmid et al.

DIABETES (2009)

Article Gastroenterology & Hepatology

Influence of Visfatin on Histopathological Changes of Non-alcoholic Fatty Liver Disease

R. Aller et al.

DIGESTIVE DISEASES AND SCIENCES (2009)

Article Biochemistry & Molecular Biology

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes

Shin-ichiro Imai et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2009)

Article Biochemistry & Molecular Biology

Crystal structure of Rattus norvegicus Visfatin/PBEF/Nampt in complex with an FK866-based inhibitor

Gil Bu Kang et al.

MOLECULES AND CELLS (2009)

Article Biochemistry & Molecular Biology

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

Frederic Van Gool et al.

NATURE MEDICINE (2009)

Article Endocrinology & Metabolism

A Rare Variant in the Visfatin Gene (NAMPT/PBEF1) Is Associated With Protection From Obesity

Alexandra I. F. Blakemore et al.

OBESITY (2009)

Article Multidisciplinary Sciences

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

Yasukazu Nakahata et al.

SCIENCE (2009)

Article Multidisciplinary Sciences

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD(+) Biosynthesis

Kathryn Moynihan Ramsey et al.

SCIENCE (2009)

Review Endocrinology & Metabolism

Nampt: linking NAD biology, metabolism and cancer

Antje Garten et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)

Article Endocrinology & Metabolism

Role of adipocytokines in predicting the development of diabetes and its late complications

Nese Ersoz Gulcelik et al.

ENDOCRINE (2009)

Article Behavioral Sciences

Central visfatin causes orexigenic effects in chicks

Mark A. Cline et al.

BEHAVIOURAL BRAIN RESEARCH (2008)

Article Biochemistry & Molecular Biology

Anticancer agent CHS-828 inhibits cellular synthesis of NAD

Uffe Hogh Olesen et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Article Biochemistry & Molecular Biology

Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase

Emmanuel S. Burgos et al.

BIOCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Extracellular Nampt Promotes Macrophage Survival via a Nonenzymatic Interleukin-6/STAT3 Signaling Mechanism

Yankun Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Transplantation

Endothelial dysfunction in type-2 diabetics with early diabetic nephropathy is associated with low circulating adiponectin

Mahmut Ilker Yilmaz et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2008)

Review Biochemistry & Molecular Biology

Metabolic adaptations through the PGC-1α and SIRT1 pathways

Joseph T. Rodgers et al.

FEBS LETTERS (2008)

Article Physiology

Visfatin: a new player in mesangial cell physiology and diabetic nephropathy

Hye Kyoung Song et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)

Article Endocrinology & Metabolism

Molecular characteristics of serum visfatin and differential detection by immunoassays

Antje Koerner et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)

Article Biochemistry & Molecular Biology

Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

Hongying Yang et al.

Article Multidisciplinary Sciences

TNF-α suppresses the expression of clock genes by interfering with E-box-mediated transcription

Gionata Cavadini et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

Visfatin is released from 3T3-L1 adipocytes via a non-classical pathway

Masaki Tanaka et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Endocrinology & Metabolism

Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children

Antje Koerner et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2007)

Article Biochemistry & Molecular Biology

Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2

Su-Ryun Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Biochemical Research Methods

Crystallization of human nicotinamide phosphoribosyltransferase

Ryo Takahashi et al.

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2007)

Article Biochemistry & Molecular Biology

Extension of human cell lifespan by nicotinamide phosphoribosyltransferase

Eric van der Veer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Endocrinology & Metabolism

TNF-α alters visfatin and adiponectin levels in human fat

J. Hector et al.

HORMONE AND METABOLIC RESEARCH (2007)

Article Endocrinology & Metabolism

Human visfatin expression: Relationship to insulin sensitivity, intramyocellular lipids, and inflammation

Vijayalakshmi Varma et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)

Article Endocrinology & Metabolism

Insulin-like effects of visfatin on human osteoblasts

H. Xie et al.

CALCIFIED TISSUE INTERNATIONAL (2007)

Article Multidisciplinary Sciences

Mechanisms linking obesity to insulin resistance and type 2 diabetes

Steven E. Kahn et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Visfatin in adipocytes is upregulated by hypoxia through HIFIα-dependent mechanism

Katsumori Segawa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Endocrinology & Metabolism

Serum visfatin increases with progressive β-cell deterioration

Abel Lopez-Bermejo et al.

DIABETES (2006)

Article Endocrinology & Metabolism

The visfatin gene is associated with glucose and lipid metabolism in a Chinese population

W. -X. Jian et al.

DIABETIC MEDICINE (2006)

Article Endocrinology & Metabolism

The release of the adipocytokine visfatin is regulated by glucose and insulin

D. G. Haider et al.

DIABETOLOGIA (2006)

Article Biochemistry & Molecular Biology

Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1

Soo-Kyung Bae et al.

FEBS LETTERS (2006)

Article Biochemistry & Molecular Biology

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme

Tao Wang et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents

Javed A. Khan et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Endocrinology & Metabolism

Increased plasma visfatin concentrations in morbidly obese subjects are reduced after gastric banding

DG Haider et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)

Article Biochemistry & Molecular Biology

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells

L Bordone et al.

PLOS BIOLOGY (2006)

Article Endocrinology & Metabolism

Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus

MP Chen et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)

Article Endocrinology & Metabolism

Interleukin-6 is a negative regulator of visfatin gene expression in 3T3-L1 adipocytes

S Kralisch et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)

Article Endocrinology & Metabolism

Hormonal regulation of the novel adipocytokine visfatin in 3T3-L1 adipocytes

S Kralisch et al.

JOURNAL OF ENDOCRINOLOGY (2005)

Article Biochemistry & Molecular Biology

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

JR Revollo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1

A van der Horst et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1

KJ Bitterman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Obstetrics & Gynecology

Pre-B-cell colony-enhancing factor, a novel cytokine of human fetal membranes

S Ognjanovic et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2002)

Article Public, Environmental & Occupational Health

Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27,485 people

B Karlsson et al.

OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2001)