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CELL (2004)
Growth phase-dependent changes in the subcellular localization of pre-B-cell colony-enhancing factor
T Kitani et al.
FEBS LETTERS (2003)
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1
KJ Bitterman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Pre-B-cell colony-enhancing factor, a novel cytokine of human fetal membranes
S Ognjanovic et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2002)
Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27,485 people
B Karlsson et al.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2001)
Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence
PR Martin et al.
JOURNAL OF BACTERIOLOGY (2001)