期刊
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
卷 28, 期 7, 页码 575-581出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10815-011-9551-7
关键词
Frozen blastocyst transfer; Frozen cycle outcome; IVF; Multiple pregnancy; Number of embryos to transfer
Purpose To evaluate clinical outcomes of frozen-thawed embryo transfer cycles when one or two blastocysts are transferred. Methods Retrospective chart review Results Two hundred forty-three frozen blastocyst transfer (FBT) cycles were analyzed. Clinical pregnancy rate (50.4% vs. 34.7%), live birth rate (45.8% vs. 30.6%), and twin live birth rate (19.3% vs. 0) were significantly higher in the double versus single FBT group, respectively (p < 0.05). Prior fresh cycle success with same-cohort embryos did not predict outcome of FBT cycle. When the fresh cycle was unsuccessful, there still was a significant increase in twinning when two frozen-thawed blastocysts were transferred. Conclusions Transferring two blastocysts during an FBT cycle resulted in higher live birth and twin live birth rates. Single FBT provided acceptable pregnancy rates for couples seeking to avoid a multiple pregnancy or for those having a single blastocyst stored. Interestingly, the outcome of fresh cycle with same-cohort embryos did not influence the outcome of frozen-thawed cycle.
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