Prediction of high ovarian response to controlled ovarian hyperstimulation: anti-Mullerian hormone versus small antral follicle count (2-6 mm)

To evaluate the predictive value of basal serum anti-mullerian hormone level and small antral follicle count for high ovarian response to controlled ovarian hyperstimulation. A total of 159 patients were prospectively included. Basal serum anti-mullerian hormone and small antral follicle count (2-6 mm) were measured. Small antral follicle count and anti-mullerian hormone have similar predictive accuracy for high ovarian response with area under curve of 0.961 and 0.922, respectively. The sensitivity and specificity for prediction of high ovarian response were 89% and 92% for small antral follicle count and 93% and 78% for anti-mullerian hormone at the cutoff values of a parts per thousand yen 16 and a parts per thousand yen 34.5 pmol/l, respectively. Small antral follicle count and anti-mullerian hormone are equally accurate predictors of high ovarian response and facilitate determination of the optimal strategy for controlled ovarian hyperstimulation.