Ionone glycosides from the roots of Rehmannia glutinosa

Four new ionone and ionone glycosides (1-4), and a new monoterpene (5), together with 10 known analogues (6-15), were isolated from the air-dried roots of Rehmannia glutinosa. The structures of these compounds were elucidated on the basis of spectroscopic data analysis. Furthermore, in in vitro assays, compound 3 (10M) exhibited moderate hepatoprotective activities against d-galactosamine-induced HL-7702 cell damage. [GRAPHICS] .