期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 17, 期 2, 页码 188-198出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2014.985770
关键词
Chinese patents; natural products; antidepressants
资金
- National Science Foundation of China for Distinguished Young Scholars [81025023]
- National Science Foundation of China [81202436]
- Youth Innovation Promotion Association, Chinese Academy of Sciences (CAS)
Depressive disorder is a severe psychiatric problem all over the world. Clinical therapeutic agents for the treatment of depression in the market targeting on monoamine neurotransmitters are far from satisfaction due to their adverse effects. Novel classes of antidepressant agents with different mechanisms and low toxicity are needed. Natural products from traditional Chinese medicines have been revealed as new sources to cure the depressive symptoms with various chemical structures and promising activities. This paper reviews natural products as antidepressants documented in Chinese patents so far.
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