期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 12, 期 6, 页码 505-515出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2010.489817
关键词
Morus cathayana; flavonoids; cytotoxic activities
资金
- National Natural Science Foundation of China [20432030]
- Basic Scientific Research Foundation of the Central Government of China [2006QN04]
- Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical College, Ministry of Education
Phytochemical investigation of the stem bark of Morus cathayana led to the isolation and identification of six new compounds, cathayanons F-J (1-5) and cathayanin A (6), and two known compounds, cathayanins B-C (7-8). Their structures were elucidated by spectroscopic methods. Compounds 1, 2, 3, 5, and 7 exhibited weak activities against five human cancer cell lines, with IC50 values ranging from 4.7 to 9.8g/ml.
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