期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 10, 期 11, 页码 1039-1043出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020802320590
关键词
portulene; rigla; Portulaca oleracea; hepatoprotective activity
Chromatographic fractionation of the chloroform extract of Portulaca oleracea L. growing in Egypt afforded a new clerodene diterpene portulene (1), in addition to the known compounds lupeol (2), -sitosterol (3), and daucosterol (4), which were reported for the first time from the title plant. The structures of the isolated compounds were unambiguously established through 1D, 2D, and mass spectral analyses. Co-treatment of CCl4 hepatic injured rats with 70% alcohol extract of P. oleracea significantly restored the hepatic marker enzymes and total bilirubin to near-normal values, which demonstrated hepatoprotective activity. In addition, the P. oleracea extract showed antibacterial and antifungal activities.
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