期刊
NATURE NEUROSCIENCE
卷 19, 期 1, 页码 37-+出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.4192
关键词
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资金
- Intramural Research Program of the National Institute of Mental Health
- Intramural Research Program of the National Cancer Institute
- PRESTO/JST
- KAKENHI [15H05917]
- Grants-in-Aid for Scientific Research [15K09979] Funding Source: KAKEN
To study how the interaction between orbitofrontal (OFC) and rhinal (Rh) cortices influences the judgment of reward size, we reversibly disconnected these regions using hM4Di-DREADD (designer receptor exclusively activated by designer drug). Repeated inactivation reduced sensitivity to differences in reward size in two monkeys. These results suggest that retrieval of relative stimulus values from memory depends on the interaction between Rh and OFC.
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