期刊
NATURE MEDICINE
卷 21, 期 10, 页码 1142-+出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nm.3953
关键词
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资金
- Stanford Institute for Neuro-Innovation and Translational Neuroscience
- Stanford BioX-NeuroVentures
- Stanford Office of Postdoctoral Affairs
- Garlick Foundation
- Craig H. Neilsen Foundation
- US National Institutes of Health: the National Institute on Deafness and Other Communication Disorders (NIDCD) [R01DC009899, R01DC014034]
- US National Institutes of Health: National Institute of Neurological Disorders and Stroke (NINDS) [RO1NS066311-S1]
- US National Institutes of Health: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)-National Center for Medical Rehabilitation Research (NCMRR) [N01HD53403, N01HD10018]
- Rehabilitation Research and Development Service, Department of Veterans Affairs [B6453R, B6310N]
- Massachusetts General Hospital (MGH)-Deane Institute for Integrated Research on Atrial Fibrillation and Stroke
Neural prostheses have the potential to improve the quality of life of individuals with paralysis by directly mapping neural activity to limb- and computer-control signals. We translated a neural prosthetic system previously developed in animal model studies for use by two individuals with amyotrophic lateral sclerosis who had intracortical microelectrode arrays placed in motor cortex. Measured more than 1 year after implant, the neural cursor-control system showed the highest published performance achieved by a person to date, more than double that of previous pilot clinical trial participants.
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