期刊
JOURNAL OF APPLIED PHYSIOLOGY
卷 110, 期 1, 页码 264-274出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/japplphysiol.00993.2010
关键词
endurance exercise; skeletal muscle adaptation; fiber type transformation; angiogenesis; mitochondrial biogenesis
资金
- National Institutes of Health [AR-050429]
- NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [R01AR050429] Funding Source: NIH RePORTER
Yan Z, Okutsu M, Akhtar YN, Lira VA. Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle. J Appl Physiol 110: 264-274, 2011. First published October 28, 2010; doi:10.1152/japplphysiol.00993.2010.-Skeletal muscle exhibits superb plasticity in response to changes in functional demands. Chronic increases of skeletal muscle contractile activity, such as endurance exercise, lead to a variety of physiological and biochemical adaptations in skeletal muscle, including mitochondrial biogenesis, angiogenesis, and fiber type transformation. These adaptive changes are the basis for the improvement of physical performance and other health benefits. This review focuses on recent findings in genetically engineered animal models designed to elucidate the mechanisms and functions of various signal transduction pathways and gene expression programs in exercise-induced skeletal muscle adaptations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据