期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 59, 期 10, 页码 6661-6664出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01103-15
关键词
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资金
- National Basic Research Program of China [2013CB127200]
- National Natural Science Foundation of China [U1031004]
Macrolides are the antimicrobials of choice for treating human campylobacteriosis. The recent emergence of erm(B) in Campylobacter bacteria threatens the utility of this class of antibiotics. Here we report the constitutive and inducible expression of erm(B) in Campylobacter isolates derived from diarrheal patients and food-producing animals. Constitutive expression of erm(B) was associated with insertion and deletion in the regulatory region of the gene, providing the first documentation of the differential expression of erm(B) in Campylobacter bacteria.
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