期刊
NATURE CELL BIOLOGY
卷 17, 期 3, 页码 204-211出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb3108
关键词
-
类别
资金
- CNRS
- Citizens United for Research in Epilepsy (CURE)
- DFG
- BMBF
- Bavarian research network Induced Pluripotent Stem Cells (ForIPS)
- Helmholtz Association
- FP7 IRG-ENDOPANC
- ERC-St. Grant HEPATOPANCREATIC
Vital organs such as the pancreas and the brain lack the capacity for effective regeneration. To overcome this limitation, an emerging strategy consists of converting resident tissue-specific cells into the cell types that are lost due to disease by a process called in vivo lineage reprogramming. Here we discuss recent breakthroughs in regenerating pancreatic beta-cells and neurons from various cell types, and highlight fundamental challenges that need to be overcome for the translation of in vivo lineage reprogramming into therapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据