期刊
NATURE CELL BIOLOGY
卷 17, 期 8, 页码 964-965出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb3212
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Mitotic chromosome condensation has fascinated biologists since Flemming's early illustrations of mitosis in the late nineteenth century. Now - 130 years later - chromatid condensation is reconstituted in vitro with the minimum components. The results are remarkably and beautifully simple, requiring only core histones, three histone chaperones, topoisomerase II and condensin I.
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