相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia
Jae-Seok Roe et al.
MOLECULAR CELL (2015)
HTSeq-a Python framework to work with high-throughput sequencing data
Simon Anders et al.
BIOINFORMATICS (2015)
A comprehensive transcriptional portrait of human cancer cell lines
Christiaan Klijn et al.
NATURE BIOTECHNOLOGY (2015)
Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors
Piro Lito et al.
CANCER CELL (2014)
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer
Irfan A. Asangani et al.
NATURE (2014)
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia
Birgit Knoechel et al.
NATURE GENETICS (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
Jakob Loven et al.
CELL (2013)
Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
Junwei Shi et al.
GENES & DEVELOPMENT (2013)
Transcriptional regulation by Polycomb group proteins
Luciano Di Croce et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;NrasG12D acute myeloid leukemia
J. Shi et al.
ONCOGENE (2013)
Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq
Cosmas D. Arnold et al.
SCIENCE (2013)
Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Alexandre Puissant et al.
CANCER DISCOVERY (2013)
An Optimized microRNA Backbone for Effective Single-Copy RNAi
Christof Fellmann et al.
CELL REPORTS (2013)
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Jordi Barretina et al.
NATURE (2012)
Fast gapped-read alignment with Bowtie 2
Ben Langmead et al.
NATURE METHODS (2012)
A pipeline for the generation of shRNA transgenic mice
Lukas E. Dow et al.
NATURE PROTOCOLS (2012)
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity
Cecilia Ballare et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Polycomb repressive complex 2 is required for MLL-AF9 leukemia
Tobias Neff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Jake E. Delmore et al.
CELL (2011)
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
Johannes Zuber et al.
GENES & DEVELOPMENT (2011)
The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3
Shaila Rahman et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Christof Fellmann et al.
MOLECULAR CELL (2011)
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Johannes Zuber et al.
NATURE (2011)
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
Mark A. Dawson et al.
NATURE (2011)
Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
Johannes Zuber et al.
NATURE BIOTECHNOLOGY (2011)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
BEDTools: a flexible suite of utilities for comparing genomic features
Aaron R. Quinlan et al.
BIOINFORMATICS (2010)
Selective inhibition of BET bromodomains
Panagis Filippakopoulos et al.
NATURE (2010)
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
Curtis A. Thorne et al.
NATURE CHEMICAL BIOLOGY (2010)
The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
Yingzi Wang et al.
SCIENCE (2010)
Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
Jeremy Goecks et al.
GENOME BIOLOGY (2010)
TopHat: discovering splice junctions with RNA-Seq
Cole Trapnell et al.
BIOINFORMATICS (2009)
Fast and accurate short read alignment with Burrows-Wheeler transform
Heng Li et al.
BIOINFORMATICS (2009)
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
James W. Vardiman et al.
BLOOD (2009)
Mouse models of human AML accurately predict chemotherapy response
Johannes Zuber et al.
GENES & DEVELOPMENT (2009)
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
Ben Langmead et al.
GENOME BIOLOGY (2009)
Mapping and quantifying mammalian transcriptomes by RNA-Seq
Ali Mortazavi et al.
NATURE METHODS (2008)
Model-based Analysis of ChIP-Seq (MACS)
Yong Zhang et al.
GENOME BIOLOGY (2008)
CRD-BP mediates stabilization of βTrCP1 and c-myc mRNA in response to β-catenin signalling
Felicite K. Noubissi et al.
NATURE (2006)
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
Ting-Chao Chou
PHARMACOLOGICAL REVIEWS (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
MK Jang et al.
MOLECULAR CELL (2005)
A role for Wnt signalling in self-renewal of haematopoietic stem cells
T Reya et al.
NATURE (2003)
ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation
FT Kolligs et al.
CANCER CELL (2002)
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
EL Jackson et al.
GENES & DEVELOPMENT (2001)
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
J Jonkers et al.
NATURE GENETICS (2001)