期刊
NATURE
卷 526, 期 7573, 页码 361-370出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nature15819
关键词
-
资金
- Cancer Research UK [17263] Funding Source: researchfish
- Wellcome Trust [103721/Z/14/Z] Funding Source: researchfish
- Wellcome Trust [103721/Z/14/Z] Funding Source: Wellcome Trust
- Wellcome Trust [103721] Funding Source: Medline
An enhanced understanding of the molecular pathology of disease gained from genomic studies is facilitating the development of treatments that target discrete molecular subclasses of tumours. Considerable associated challenges include how to advance and implement targeted drug-development strategies. Precision medicine centres on delivering the most appropriate therapy to a patient on the basis of clinical and molecular features of their disease. The development of therapeutic agents that target molecular mechanisms is driving innovation in clinical-trial strategies. Although progress has been made, modifications to existing core paradigms in oncology drug development will be required to realize fully the promise of precision medicine.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据