期刊
JOURNAL OF APPLIED MICROBIOLOGY
卷 117, 期 2, 页码 303-319出版社
WILEY
DOI: 10.1111/jam.12521
关键词
lactobacilli; mechanism; mucosal immune system; probiotics; systemic immune system
资金
- Ministry of External Affairs (Government of India)
- African Union
The mechanism by which probiotic lactobacilli affect the immune system is strain specific. As the immune system is a multicompartmental system, each strain has its way to interact with it and induce a visible and quantifiable effect. This review summarizes the interplay existing between the host immune system and probiotic lactobacilli, that is, with emphasis on lactobacilli as a prototype probiotic genus. Several aspects including the bacterial-host crosstalk with the mucosal and systemic immune system are presented, as well as short sections on the competing effect towards pathogenic bacteria and their uses as delivery vehicle for antigens.
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