期刊
NATURAL PRODUCT RESEARCH
卷 29, 期 23, 页码 2167-2180出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1007455
关键词
usnic acid; lichen; biological activity; antioxidant; antimicrobial
资金
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico/CNPq/Brazil)
- Fundacao de Amparo a Pesquisa do Estado de Sergipe/FAPITEC-SE
Since its first isolation in 1844, usnic acid [2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl1,3(2H, 9bH)-dibenzo-furandione] has become the most extensively studied lichen metabolite and one of the few that are commercially available. Lichens belonging to usnic acid-containing genera have been used as crude drugs throughout the world. There are indications of usnic acid being a potentially interesting candidate for such activities as anti-inflammatory, analgesic, healing, antioxidant, antimicrobial, antiprotozoal, antiviral, larvicidal and UV protection. However, some studies reported the liver toxicity and contact allergy. Thus, further studies are needed to establish the efficacy and safety of usnic acid
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