4.4 Article

A new aldehyde compound from the fruit of Pandanus tectorius Parkinson ex Du Roi

期刊

NATURAL PRODUCT RESEARCH
卷 29, 期 15, 页码 1437-1441

出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2014.1003929

关键词

Pandanus tectorius; alpha-glucosidase; new aldehyde

资金

  1. Vietnam National Foundation for Science and Technology Development (NAFOSTED) [104.01-2012.72]

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From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new (1) and six known aldehyde compounds (2-7) were isolated by various chromatography methods. Based on their spectroscopic data, these compounds were identified as (Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl) benzaldehyde (1), p-hydroxybenzaldehyde (2), syringaldehyde (3), (E)-ferulaldehyde (4), (E)-sinapinaldehyde (5), vanillin (6) and 5-hydroxymethylfurfual (7). The alpha-glucosidase inhibitory activity of all compounds was measured. The isolated compounds (1-6) showed better alpha-glucosidase inhibitory activity (IC50 values ranging from 36.5 to 192.4 mu M) than the standard drug acarbose (IC50=214.5 mu M).

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