4.4 Article

Two new compounds from cultures of the basidiomycete Antrodiella albocinnamomea

期刊

NATURAL PRODUCT RESEARCH
卷 29, 期 21, 页码 1985-1989

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TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1017493

关键词

sesquiterpene; linear triterpene; Antrodiella albocinnamomea; protein tyrosine phosphatase 1B

资金

  1. Research Foundation for Advanced Talents, Lingnan Normal University [ZL1403]

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A new linear triterpene (1), and a new sesquiterpene (2), together with a known compound methyl indole-3-carboxylate (3) were isolated from the crude extract of Antrodiella albocinnamomea. The structures of the new compounds 1-2 were determined by comprehensive spectroscopic analysis. Compound 1 exhibited signi?cant inhibitory activities against protein tyrosine phosphatase 1B (PTP1B) with IC50 value of 1.0 mu g/mL.

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