期刊
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
卷 63, 期 -, 页码 I36-I40出版社
OXFORD UNIV PRESS
DOI: 10.1093/jac/dkp081
关键词
mucosal barrier injury; innate immunity; inflammation; cancer treatment; infections
The treatment of patients with cancer is often accompanied by life-threatening complications caused by chemotherapy and radiotherapy. They are known to result from neutropenia, but damage to the mucosal barrier as well as the humoral and cellular immune defences play a significant role in various infectious complications and aggravate diverse inflammatory processes. The article describes the journey from febrile neutropenia to febrile mucositis in patients treated with immunocompromising therapy.
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