期刊
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
卷 61, 期 4, 页码 805-809出版社
OXFORD UNIV PRESS
DOI: 10.1093/jac/dkn022
关键词
elongation factor alpha; antifungal resistance; emerging moulds
Objectives: To analyse the susceptibility pattern of a collection of Fusarium clinical isolates. Methods: The antifungal susceptibility pattern of 67 isolates of Fusarium was analysed. Strains were identified by morphological and molecular methods by means of sequencing elongation factor alpha. Results and conclusions: Six different species were identified. Fusarium solani was the most frequently isolated, followed by Fusarium oxysporum, Fusarium proliferatum and Fusarium verticilloides. Amphotericin B was the only drug with in vitro activity (range: 0.015-32 mg/L). The rest of the antifungals tested (itraconazole, voriconazole, ravuconazole, posaconazole and terbinafine) showed very poor activity against Fusarium, confirming the multiresistant nature of this genus.
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