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Two new amides from a halotolerant fungus, Myrothecium sp GS-17

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JOURNAL OF ANTIBIOTICS
卷 68, 期 4, 页码 267-270

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JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2014.136

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  1. National Natural Science Foundation of China [20872094]

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Two new amides, named N-acetyl-2,4,10,17-tetrahydroxyheptadecylamine (1) and N-acetyl-3,5,11,18-tetrahydroxyoctadecyl-2-amine (2), were isolated from a halotolerant fungus, Myrothecium sp. GS-17. Their structures were identified on the basis of spectroscopic characteristics. The cancer cell cytotoxicities of two compounds were evaluated, and compound 2 exhibited weak cytotoxicity in HL-60 cell line.

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