期刊
JOURNAL OF ANTIBIOTICS
卷 65, 期 7, 页码 355-359出版社
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2012.30
关键词
Actinomadura; polyketide; spirotetronate
Nomimicin (1), a new spirotetronate-class polyketide, was isolated from the culture broth of an actinomycete of the genus Actinomadura. Its structure was established by spectroscopic methods, and the absolute configuration was determined by a combination of NOESY experiment, J-based configuration analysis and the modified Mosher method. Nomimicin (1) showed antimicrobial activity against Micrococcus luteus, Candida albincans and Kluyveromyces fragilis. The Journal of Antibiotics (2012) 65, 355-359; doi: 10.1038/ja.2012.30; published online 25 April 2012
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