4.5 Review

Molecular basis for the actions of Hsp90 inhibitors and cancer therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Medicinal

Synthesis and in vitro anti-HSV-1 activity of a novel Hsp90 inhibitor BJ-B11

Huai-Qiang Ju et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)

Article Biochemistry & Molecular Biology

p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC

N. R. Christoffersen et al.

CELL DEATH AND DIFFERENTIATION (2010)

Article Biochemistry & Molecular Biology

Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth

S. Chandarlapaty et al.

ONCOGENE (2010)

Article Multidisciplinary Sciences

Dynamics of heat shock protein 90 C-terminal dimerization is an important part of its conformational cycle

C. Ratzke et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Cell Biology

Hsp90 Regulates the Function of Argonaute 2 and Its Recruitment to Stress Granules and P-Bodies

Justin M. Pare et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Article Multidisciplinary Sciences

Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

Eloisi Caldas-Lopes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Pharmacology & Pharmacy

ROMIDEPSIN FOR THE TREATMENT OF CUTANEOUS T-CELL LYMPHOMA

Clara Campas-Moya

DRUGS OF TODAY (2009)

Review Biochemistry & Molecular Biology

The Hsp90 molecular chaperone: an open and shut case for treatment

Laurence H. Pearl et al.

BIOCHEMICAL JOURNAL (2008)

Article Cell Biology

Control of cell proliferation pathways by microRNAs

Maria Jose Bueno et al.

CELL CYCLE (2008)

Review Biochemistry & Molecular Biology

Novobiocin and Additional Inhibitors of the Hsp90 C-Terminal Nucleotide-binding Pocket

Alison Donnelly et al.

CURRENT MEDICINAL CHEMISTRY (2008)

Review Pharmacology & Pharmacy

Targeting Hsp90: small-molecule inhibitors and their clinical development

Tony Taldone et al.

CURRENT OPINION IN PHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

Quercetin-induced ubiquitination and down-regulation of Her-2/neu

Jae-Hoon Jeong et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2008)

Article Chemistry, Medicinal

Optimizing natural products by biosynthetic engineering: Discovery of nonquinone Hsp90 inhibitors

Ming-Qiang Zhang et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Article Chemistry, Medicinal

Molecular characterization of macbecin as an Hsp90 inhibitor

Christine J. Martin et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Article Oncology

Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function

Shashwati Basak et al.

MOLECULAR CANCER THERAPEUTICS (2008)

Editorial Material Biochemistry & Molecular Biology

Targeting RAS and PI3K in lung cancer

Julian Downward

NATURE MEDICINE (2008)

Article Multidisciplinary Sciences

AP4 encodes a c-MYC-inducible repressor of p21

Peter Jung et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion

S. Tsutsumi et al.

ONCOGENE (2008)

Article Oncology

Translocation of heparanase into nucleus results in cell differentiation

Tetsuji Nobuhisa et al.

CANCER SCIENCE (2007)

Article Biochemistry & Molecular Biology

Regulation of c-Src activity by the expression of wild-type v-Src and its kinase-dead double Y416F-K295N mutant

Martina Vojtechova et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2006)

Article Biochemistry & Molecular Biology

The middle domain of Hsp90 acts as a discriminator between different types of client proteins

Patricija Hawle et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Oncology

Differentially active origins of DNA replication in tumor versus normal cells

Domenic Di Paola et al.

CANCER RESEARCH (2006)

Article Pharmacology & Pharmacy

let-7 microRNA functions as a potential growth suppressor in human colon cancer cells

Yukihiro Akao et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2006)

Review Biochemistry & Molecular Biology

Heat shock proteins in cancer: chaperones of tumorigenesis

SK Calderwood et al.

TRENDS IN BIOCHEMICAL SCIENCES (2006)

Article Oncology

Angiostatic activity of DNA methyltransferase inhibitors

DMEI Hellebrekers et al.

MOLECULAR CANCER THERAPEUTICS (2006)

Article Biotechnology & Applied Microbiology

The HSP90 family of genes in the human genome: Insights into their divergence and evolution

B Chen et al.

GENOMICS (2005)

Review Multidisciplinary Sciences

Ribo-gnome: The big world of small RNAs

PD Zamore et al.

SCIENCE (2005)

Article Oncology

Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway

MT McCabe et al.

CANCER RESEARCH (2005)

Article Biochemistry & Molecular Biology

CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone, Cdc37

Y Miyata et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Chemistry, Medicinal

Synthesis and antitumor activity of novel O-carbamoylmethyloxime derivatives of radicicol

Y Ikuina et al.

JOURNAL OF MEDICINAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Identification of a cis-element that determines autonomous DNA replication in eukaryotic cells

GB Price et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

Direct activation of RNA polymerase III transcription by c-Myc

N Gomez-Roman et al.

NATURE (2003)

Article Biochemistry & Molecular Biology

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1

N Fujita et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)