期刊
JOURNAL OF ANTIBIOTICS
卷 64, 期 2, 页码 193-196出版社
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2010.154
关键词
Aspergillus versicolor; deep-sea; fungus; sterigmatocystin
资金
- Chinese National Science Fund [30772640, 30973627]
- Shandong Provincial Natural Science Fund [ZR2009CZ016]
Three new sterigmatocystin derivatives, oxisterigmatocystin A (1), oxisterigmatocystin B (2) and oxisterigmatocystin C (3), together with one known compound, 5-methoxysterigmatocystin (4), were isolated from the deep-sea-derived fungus Aspergillus versicolor. The structures of the new compounds were elucidated by spectroscopic methods. The cytotoxicities of compounds 1-4 were evaluated against the A-549 and HL-60 cell lines. Compound 4 exhibited moderate cytotoxicities against the A-549 and HL-60 cell lines with IC(50) value of 3.86 and 5.32 mu m, respectively. The Journal of Antibiotics (2011) 64, 193-196; doi:10.1038/ja.2010.154; published online 1 December 2010
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