期刊
JOURNAL OF ANATOMY
卷 215, 期 1, 页码 3-13出版社
WILEY
DOI: 10.1111/j.1469-7580.2008.01034.x
关键词
adhesion; embryo; endometrium; epithelium; implantation
Cell adhesion in endometrial epithelium is regulated to maintain the continuity and protectiveness of the luminal covering cell layer while permitting interstitial implantation of the embryo during a restricted period of about 4 days. Many apparently normal embryos fail to implant, and epithelial-embryo adhesion remains a poorly understood phenomenon. After menstruation, epithelial regeneration occurs by epiboly from the basal residues of glands, an activity that requires migration on extracellular matrix as well as cell-cell cohesion. Here we review current knowledge of adhesion molecules in the epithelium.
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