期刊
JOURNAL OF ALZHEIMERS DISEASE
卷 42, 期 -, 页码 S329-S338出版社
IOS PRESS
DOI: 10.3233/JAD-141413
关键词
Alzheimer's disease; cognition; dementia; early diagnosis; screening
资金
- National Institute for Health Research [NF-SI-0611-10084] Funding Source: researchfish
Accurate detection of individuals with cognitive impairment and dementia in addition to identification of those at high risk of future disease is important to guide clinical care, and has research implications regarding clinical trial recruitment and development of dementia preventative strategies. In this narrative review, we describe new proposed criteria for early diagnosis of Alzheimer's disease (AD). We also explore risk factors for dementia and evaluate methods for screening for increased risk of incident disease. We highlight variability in different diagnostic approaches. Additional work needs to be done to validate new methods across different settings (such as population-based, primary care, and memory clinics), age, and ethnic groups. Having an accurate method to assess for dementia and predict risk in routine clinical care will aid decision making and could ultimately lead to disease prevention.
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