Nano/submicron-scale TiO2 network on titanium surface for dental implant application

In this study, a fast electrochemical anodization treatment, applying different anodic currents, was used to produce a nano/submicron-scale network oxide layer on Ti metal surface for biomedical implant application. The anodized Ti surface was analyzed using thin film X-ray diffractometer, X-ray photoelectron spectrometer, and field emission scanning electron microscope. The whole blood coagulation and human bone marrow stem cells (hBMSCs) adhesion on the anodized Ti surface were evaluated. Results showed that a nano/submicron-scale TiO2 network layer with a lateral pore size of 20-160 nm could be rapidly produced on Ti surface through electrochemical anodization treatment. Increasing the applied anodic current led to an increase in pore size of TiO2 network. The nano/submicron-scale TiO2 network layer significantly enhanced the whole blood coagulation and hBMSCs adhesion on Ti surface. (C) 2009 Elsevier B.V. All rights reserved.