期刊
NANO TODAY
卷 10, 期 6, 页码 717-736出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.nantod.2015.11.004
关键词
Selenium-containing polymer; Tellurium-containing polymer; Self-assembly; Nano-materials; Controlled delivery; Stimuli response
资金
- National Basic Research Program of China [2013CB834502]
- National Science Foundation for Distinguished Young Scholars [21425416]
- National Natural Science Foundation of China [91427301]
- Foundation for Innovative Research Groups of the National Natural Science Foundation of China [21421064]
Selenium/tellurium containing polymers have been attracting growing interest due to their unique properties and potential applications as bio-nanomaterials. The introduction of selenium or tellurium chemistry into block copolymers endows self-assembled nanomaterials with novel stimuli responsiveness and enhanced sensitivity. This review article provides an overview on recent advances of selenium/tellurium containing polymers. We summarize the redox response and reversible self-assembly behaviors, gamma-ray responsive systems for combined chemo- and radio-therapies, and coordination-responsive systems for controlled delivery are highlighted. The review then reveals how selenium-containing polymers can modulate reactive oxygen species and work as gene delivery vehicles or self-delivery therapeutics. (C) 2015 Elsevier Ltd. All rights reserved.
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