期刊
NANO LETTERS
卷 15, 期 6, 页码 3859-3864出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.nanolett.5b00693
关键词
Septin; cytoskeleton; superresolution microscopy; single molecule; DNA origami
类别
资金
- NCCR Neural Plasticity and Repair
- Holcim Foundation
- Swiss National Fund
- EMBO
- Boehringer Ingelheim
- Marie Curie Fellowship
- NCCBI
- Federal Ministry of Education and Research (BMBF, VDI) [13N11461]
- National Science Foundation [MCB-507511]
- National Institutes of Health [GM100160]
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [1212400] Funding Source: National Science Foundation
We resolved the organization of subunits in cytoskeletal polymers in cells by light microscopy. Septin GTPases form linear complexes of about 32 nm length that polymerize into filaments. We visualized both termini of septin complexes by single molecule microscopy in vitro. Complexes appeared as 32 nm spaced localization pairs, and filaments appeared as stretches of equidistant localizations. Cellular septins were resolved as localization pairs and thin stretches of equidistant localizations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据