4.7 Article

Investigation into the Occurrence in Food of Veterinary Medicines, Pharmaceuticals, and Chemicals Used in Personal Care Products

期刊

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 62, 期 17, 页码 3651-3659

出版社

AMER CHEMICAL SOC
DOI: 10.1021/jf4052418

关键词

emerging contaminants; human pharmaceuticals; veterinary medicines; personal care products; food; uptake; LC-MS/MS; GC-HRMS

资金

  1. U.K. Food Standards Agency [FS241004]
  2. Spanish Ministry of Education, Culture and Sport (National Programme for Human Resources Mobility R&D and Innovation)

向作者/读者索取更多资源

Human exposure to emerging contaminants by indirect routes is of increasing interest. This study assessed the contamination of food by chemicals used in human pharmaceuticals (HPs), veterinary medicines (VMs), and personal care products (PCPs). A prioritization study was undertaken to identify the chemicals and food-producing scenarios most likely to result in contamination of food. Around 400 samples of mushrooms, vegetables, aquaculture products, and animal tissues were collected from sites in the United Kingdom, along with aquaculture products imported from Southeast Asia. A number of multianalyte methods were developed and validated for the analysis of the prioritized compounds in these samples. The analysis of all sample method combinations required approximately 18000 determinations. Around 325 individual residues, including parabens, musk compounds, and antibiotics, were detected in 118 individual samples, but mostly at low nanograms per gram concentrations. Results suggest that the limited contamination of target chemicals occurred in the realistic food-producing scenarios investigated.

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