期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 62, 期 12, 页码 2631-2637出版社
AMER CHEMICAL SOC
DOI: 10.1021/jf500788t
关键词
Coffea arabica var. yunnanensis; roasted coffee beans; diterpenoids; structural elucidation; cytotoxicities
资金
- Research Foundation of Coffee Engineering Research Centre of CHINA [2013P001]
- National Special Program of Basic Research [SB2007FY400]
- Knowledge Innovation Program of CAS [Qian-2011]
- Foundation of Yunnan Tobacco Industry Group
- State Key Laboratory of Phytochemistry and Plant Resources in West China [P2010-ZZ14]
Five new diterpenoid glucosides, named mascaroside I (1), mascaroside II (2), paniculoside VI (3), cofaryloside 1 (4), and villanovane I (5), along with seven known ent-kaurane diterpenoid glucosides (6-12) were isolated from acetone extracts of the roasted coffee beans of Coffea arabica var. yunnanensis. Their structures were established by extensive spectroscopic analysis including 1D and 2D NMR (HSQC, HMBC, COSY, and ROESY) and by comparison with published data. Cytotoxicities evaluation of the isolates showed that they were inactive against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells.
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