期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 60, 期 46, 页码 11525-11532出版社
AMER CHEMICAL SOC
DOI: 10.1021/jf302169u
关键词
Plantago asiatica L.; polysaccharide; short-chain fatty acids; colonic content moisture; colon pH
资金
- Key Program of National Natural Science Foundation of China [31130041]
- National Natural Science Foundation of China [20802032, 21062012]
- National Key Technology R & D Program of China [2012BAD33B06]
- Objective-Oriented Project of State Key Laboratory of Food Science and Technology [SKLF-MB-201001]
- Training Project of Young Scientists of Jiangxi Province (Stars of Jing gang)
Mice (20.0 +/- 2.0 g, n = 48 per group) were given 30 days oral administration of polysaccharide-from Plantago asiatica L. seeds at the dose of 04 g/kg body weight by gavage to investigate the effects of the polysaccharide on mouse colon. Results showed that the concentrations of total short-chain fatty acids (SCFA), acetic, propionic, and n-butyric acids in mouse colonic content of polysaccharide treated group were all significantly higher than that of control group (water) (p < 0.05). In addition, moisture of mouse colonic content of polysaccharide treated group was also notably higher than that of the control group (p < 0.05) indicating the intake of polysaccharide from P. asiatica L. resulted in a stronger water-holding capacity for colonic content throughout the experimental period. Furthermore, a decreased pH (from 7.5 +/- 0.1 to 7.2 +/- 0.1) was observed in mouse colon of the polysaccharide treated group compared with the control group (pH from 7.5 +/- 0.1 to 7.5 +/- 0.1). These results suggested that the intake of the polysaccharide from P. asiatica L. might be beneficial for the colon health.
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