期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 59, 期 1, 页码 138-144出版社
AMER CHEMICAL SOC
DOI: 10.1021/jf103130a
关键词
Antioxidant activity; alpha-glucosidase inhibitory effect; Hippophae rhamnoides; kaempferol-3-O-beta-D-(6 ''-O-coumaryl) glycoside; quercetin 3-O-beta-D-glucopyranoside
资金
- Oriental Bioherb Research Institute, Kangwon National University, Korea
This study was performed to evaluate the antioxidant and a-glucosidase inhibitory effects from the extract, fractions, and isolated compounds of sea buckthorn leaves. Six compounds, kaempferol-3-O-beta-D-(6-O-coumaryl) glycoside, 1-feruloyl-beta-D-glucopyranoside, isorhamnetin-3-O-glucoside, quercetin 3-O-beta-D-glucopyranoside, quertetin 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside, and isorhamnetin-3-O-rutinoside, were isolated from sea buckthorn leaf extracts. The butanol fraction (EC50 = 1.81 mu g/mL) along with quercetin 3-O-beta-D-glucopyranoside (EC50 = 1.86 mu g/mL) had a higher DPPH radical-scavenging activity and showed stronger reducing power (OD700 = 1.83 and 1.78, respectively). The butanol fraction (477 mg GAE/g) contained the highest amount of phenolic compounds and also the most powerful alpha-glucosidase inhibitory effect (86%) at 5 mu g/mL. The results indicate that sea buckthorn leaf extracts could potentially be used for food additives and the development of useful natural compounds.
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