期刊
JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY
卷 24, 期 13-14, 页码 2257-2270出版社
TAYLOR & FRANCIS LTD
DOI: 10.1163/016942410X508000
关键词
Femtosecond laser fabrication; titanium; surface topography; contact angle; fibroblast; osteoblast
资金
- German Research Foundation, DFG [SFB599, TR37]
In this work we present an in vitro study of the influence of two types of femtosecond laser generated topographies on a titanium surface - grooves with different periodicities and lotus-like structures - on the behavior of human fibroblast and MG-63 osteoblast cells. We show that anisotropy in wetting of groove structures correlates well with contact guidance of cells. The lotus-like structured titanium surfaces show superhydrophobic properties and influence differentially osteoblast and fibroblast adhesion and growth. The proliferation of fibroblast cells is inhibited, whereas the proliferation of osteoblast cells is promoted. This technique for cell specific control offers promising perspectives in fabrication of new functionalized implants. (C) Koninklijke Brill NV, Leiden, 2010
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