4.6 Review

Therapeutic Advances in Huntington's Disease

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Review Clinical Neurology

Deep brain stimulation in Huntington's disease: Assessment of potential targets

Mayur Sharma et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2015)

Article Clinical Neurology

Mutant Huntingtin is Present in Neuronal Grafts in Huntington Disease Patients

Francesca Cicchetti et al.

ANNALS OF NEUROLOGY (2014)

Article Pharmacology & Pharmacy

The Role of Oxidative Stress in Huntington's Disease: Are Antioxidants Good Therapeutic Candidates?

Joana Gil-Mohapel et al.

CURRENT DRUG TARGETS (2014)

Article Clinical Neurology

Deep brain stimulation for Huntington's disease: long-term results of a prospective open-label study

Victoria Gonzalez et al.

JOURNAL OF NEUROSURGERY (2014)

Article Clinical Neurology

Results of the Citalopram to Enhance Cognition in Huntington Disease Trial

Leigh J. Beglinger et al.

MOVEMENT DISORDERS (2014)

Review Clinical Neurology

Targets for Future Clinical Trials in Huntington's Disease: What's in the Pipeline?

Edward J. Wild et al.

MOVEMENT DISORDERS (2014)

Letter Medicine, Research & Experimental

Bilateral Globus Pallidus Stimulation in Westphal Variant of Huntington Disease

Giuliana Cislaghi et al.

NEUROMODULATION (2014)

Review Clinical Neurology

Review: The fate of cell grafts for the treatment of Huntington's disease: the post-mortem evidence

G. Cisbani et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2014)

Review Clinical Neurology

Treatment of Huntington's Disease

Samuel Frank

NEUROTHERAPEUTICS (2014)

Letter Clinical Neurology

A 5-year follow-up of deep brain stimulation in Huntington's disease

Jose Luis Lopez-Sendon Moreno et al.

PARKINSONISM & RELATED DISORDERS (2014)

Article Clinical Neurology

A Randomized, Double-Blind, Placebo-Controlled Trial of Pridopidine in Huntington's Disease

Karl Kieburtz et al.

MOVEMENT DISORDERS (2013)

Review Psychiatry

Acetylcholinesterase inhibitors in cognitive impairment in Huntington's disease: A brief review

Joe John Vattakatuchery et al.

WORLD JOURNAL OF PSYCHIATRY (2013)

Article Clinical Neurology

Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination

Wolfgang Brueck et al.

ACTA NEUROPATHOLOGICA (2012)

Article Multidisciplinary Sciences

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Alba Di Pardo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice

Mireia Garriga-Canut et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Endocrinology & Metabolism

External globus pallidus stimulation modulates brain connectivity in Huntington's disease

Noemie Ligot et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)

Article Neurosciences

Constitutive Upregulation of Chaperone-Mediated Autophagy in Huntington's Disease

Hiroshi Koga et al.

JOURNAL OF NEUROSCIENCE (2011)

Article Clinical Neurology

AFQ056 Treatment of Levodopa-Induced Dyskinesias: Results of 2 Randomized Controlled Trials

Daniela Berg et al.

MOVEMENT DISORDERS (2011)

Article Neurosciences

Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice

Danielle A. Simmons et al.

NEUROBIOLOGY OF DISEASE (2011)

Review Neurosciences

Dopamine and Glutamate in Huntington's Disease: A Balancing Act

Veronique M. Andre et al.

CNS NEUROSCIENCE & THERAPEUTICS (2010)

Article Biochemistry & Molecular Biology

Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo

Justin Legleiter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Clinical Neurology

A Futility Study of Minocycline in Huntington's Disease

Heidi Schwarz et al.

MOVEMENT DISORDERS (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Riluzole protects Huntington disease patients from brain glucose hypometabolism and grey matter volume loss and increases production of neurotrophins

Ferdinando Squitieri et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2009)

Article Biochemistry & Molecular Biology

Mutant huntingtin interacts with β-tubulin and disrupts vesicular transport and insulin secretion

Ruben Smith et al.

HUMAN MOLECULAR GENETICS (2009)

Article Biochemistry & Molecular Biology

Mutant Huntingtin N-terminal Fragments of Specific Size Mediate Aggregation and Toxicity in Neuronal Cells

Tamara Ratovitski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Review Clinical Neurology

A study of chorea after tetrabenazine withdrawal in patients with Huntington disease

Samuel Frank et al.

CLINICAL NEUROPHARMACOLOGY (2008)

Review Clinical Neurology

Symptomatic treatment of Huntington disease

Octavian R. Adam et al.

NEUROTHERAPEUTICS (2008)

Review Neurosciences

Transcriptional signatures in Huntington's disease

Jang-Ho J. Cha

PROGRESS IN NEUROBIOLOGY (2007)

Review Neurosciences

Role of brain-derived neurotrophic factor in Huntington's disease

Chiara Zuccato et al.

PROGRESS IN NEUROBIOLOGY (2007)

Article Medicine, Research & Experimental

Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase

M Borrell-Pagès et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Neurosciences

Minocycline in phenotypic models of Huntington's disease

K Bantubungi et al.

NEUROBIOLOGY OF DISEASE (2005)

Article Clinical Neurology

Paroxetine retards disease onset and progression in huntingtin mutant mice

WZ Duan et al.

ANNALS OF NEUROLOGY (2004)

Article Biochemistry & Molecular Biology

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease

M Tanaka et al.

NATURE MEDICINE (2004)

Article Multidisciplinary Sciences

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

C Zuccato et al.

SCIENCE (2001)