4.6 Review

Active immunization therapies for Parkinson's disease and multiple system atrophy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

Evaluation of an α synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson disease

Kenneth E. Ugen et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2015)

Review Immunology

Dendritic cell-based vaccine efficacy: aiming for hot spots

Gabriela Andrea Pizzurro et al.

FRONTIERS IN IMMUNOLOGY (2015)

Review Immunology

Regulatory T cells in cancer immunotherapy

Hiroyoshi Nishikawa et al.

CURRENT OPINION IN IMMUNOLOGY (2014)

Article Multidisciplinary Sciences

The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease

Senthilkumar S. Karuppagounder et al.

SCIENTIFIC REPORTS (2014)

Article Clinical Neurology

Alzheimer's disease drug-development pipeline: few candidates, frequent failures

Jeffrey L. Cummings et al.

ALZHEIMERS RESEARCH & THERAPY (2014)

Article Immunology

Chaperoned amyloid proteins for immune manipulation: α-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype

Adahir Labrador-Garrido et al.

IMMUNITY INFLAMMATION AND DISEASE (2014)

Review Clinical Neurology

Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion-Like Disorder?

C. Warren Olanow et al.

MOVEMENT DISORDERS (2013)

Review Pharmacology & Pharmacy

Immunotherapy for neurodegenerative diseases: Focus on α-synucleinopathies

Elvira Valera et al.

PHARMACOLOGY & THERAPEUTICS (2013)

Article Multidisciplinary Sciences

Transmission of multiple system atrophy prions to transgenic mice

Joel C. Watts et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Clinical Neurology

Molecular events underlying Parkinson's disease - an interwoven tapestry

Kah-Leong Lim et al.

FRONTIERS IN NEUROLOGY (2013)

Article Neurosciences

The Usefulness and Challenges of Transgenic Mouse Models in the Study of Alzheimers Disease

Donna M. Wilcock

CNS & Neurological Disorders-Drug Targets (2012)

Article Neurosciences

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Karin M. Danzer et al.

MOLECULAR NEURODEGENERATION (2012)

Editorial Material Clinical Neurology

Toward a Redefinition of Parkinson's Disease

Matthew B. Stern et al.

MOVEMENT DISORDERS (2012)

Review Immunology

The role of heat shock proteins in antigen cross presentation

Ayesha Murshid et al.

FRONTIERS IN IMMUNOLOGY (2012)

Editorial Material Clinical Neurology

Clinico-pathological correlations in neurodegeneration

Kurt A. Jellinger et al.

ACTA NEUROPATHOLOGICA (2011)

Article Clinical Neurology

Cerebrospinal Fluid Biomarkers for Parkinson Disease Diagnosis and Progression

Min Shi et al.

ANNALS OF NEUROLOGY (2011)

Review Genetics & Heredity

Experimental and Clinical Application of Plasmid DNA in the Field of Central Nervous Diseases

Munehisa Shimamura et al.

CURRENT GENE THERAPY (2011)

Review Pharmacology & Pharmacy

Immunotherapy for Alzheimer's Disease: Rational Basis in Ongoing Clinical Trials

Manuel Menendez-Gonzalez et al.

CURRENT PHARMACEUTICAL DESIGN (2011)

Article Biochemistry & Molecular Biology

Dopamine promotes formation and secretion of non-fibrillar alpha-synuclein oligomers

He-Jin Lee et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2011)

Article Biochemistry & Molecular Biology

Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease

Wenbo Zhou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Clinical Neurology

The natural history of treated Parkinson's disease in an incident, community based cohort

Jonathan R. Evans et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2011)

Review Multidisciplinary Sciences

Molecular chaperones in protein folding and proteostasis

F. Ulrich Hartl et al.

NATURE (2011)

Review Biotechnology & Applied Microbiology

Priorities in Parkinson's disease research

Wassilios G. Meissner et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Article Clinical Neurology

Vaccination for Parkinson's disease

A. Schneeberger et al.

PARKINSONISM & RELATED DISORDERS (2011)

Review Biotechnology & Applied Microbiology

AFFITOME® technology in neurodegenerative diseases The doubling advantage

Achim Schneeberger et al.

HUMAN VACCINES (2010)

Article Neurosciences

Genome-wide association studies: the key to unlocking neurodegeneration?

Sonia Gandhi et al.

NATURE NEUROSCIENCE (2010)

Article Multidisciplinary Sciences

Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function

Han Seok Ko et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Jan Bieschke et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Clinical Neurology

SNCA Variants Are Associated with Increased Risk for Multiple System Atrophy

Sonja W. Scholz et al.

ANNALS OF NEUROLOGY (2009)

Article Geriatrics & Gerontology

Exploratory activity and motor coordination in old versus middle-aged C57BL/6J mice

R. Lalonde et al.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2009)

Article Biochemistry & Molecular Biology

Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/α-synuclein complex by Hip

Cintia Roodveldt et al.

EMBO JOURNAL (2009)

Article Genetics & Heredity

Genome-wide association study reveals genetic risk underlying Parkinson's disease

Javier Simon-Sanchez et al.

NATURE GENETICS (2009)

Article Multidisciplinary Sciences

Genetic Variants of the α-Synuclein Gene SNCA Are Associated with Multiple System Atrophy

Ammar Al-Chalabi et al.

PLOS ONE (2009)

Article Clinical Neurology

Neuropathology of non-motor features of Parkinson disease

Dennis W. Dickson et al.

PARKINSONISM & RELATED DISORDERS (2009)

Article Clinical Neurology

Genomic investigation of α-synuclein multiplication and parkinsonism

Owen A. Ross et al.

ANNALS OF NEUROLOGY (2008)

Article Neurosciences

Olfactory deficits in mice overexpressing human wildtype α-synuclein

Sheila M. Fleming et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2008)

Article Multidisciplinary Sciences

Nitrated α-Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons

Eric J. Benner et al.

PLOS ONE (2008)

Review Pharmacology & Pharmacy

Transgenic animal models of neurodegenerative diseases and their application to treatment development

Edward Rockenstein et al.

ADVANCED DRUG DELIVERY REVIEWS (2007)

Article Multidisciplinary Sciences

Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice

Andreas Muhs et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Medicine, Research & Experimental

Diagnosis and treatment of Parkinson disease: molecules to medicine

Joseph M. Savitt et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Clinical Neurology

Grading of neuropathology in multiple system atrophy: Proposal for a novel scale

KA Jellinger et al.

MOVEMENT DISORDERS (2005)

Article Biochemistry & Molecular Biology

Heat shock protein 70 inhibits α-synuclein fibril formation via preferential binding to prefibrillar species

MM Dedmon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Neurosciences

Lipid rafts mediate the synaptic localization of α-synuclein

DL Fortin et al.

JOURNAL OF NEUROSCIENCE (2004)

Article Clinical Neurology

Active Immunization of Mice with an A beta-Hsp70 Vaccine

Michael F. Koller et al.

NEURODEGENERATIVE DISEASES (2004)

Article Multidisciplinary Sciences

α-synuclein locus triplication causes Parkinson's disease

AB Singleton et al.

SCIENCE (2003)

Review Geriatrics & Gerontology

Staging of brain pathology related to sporadic Parkinson's disease

H Braak et al.

NEUROBIOLOGY OF AGING (2003)

Review Neurosciences

Pathogenesis of Parkinson's disease:: Dopamine, vesicles and α-synuclein

J Lotharius et al.

NATURE REVIEWS NEUROSCIENCE (2002)

Article Multidisciplinary Sciences

Cerebellar role in fear-conditioning consolidation

B Sacchetti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Review Immunology

Roles of heat-shock proteins in innate and adaptive immunity

P Srivastava

NATURE REVIEWS IMMUNOLOGY (2002)

Article Multidisciplinary Sciences

β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

E Masliah et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Review Clinical Neurology

Synucleinopathies - Clinical and pathological implications

JE Galvin et al.

ARCHIVES OF NEUROLOGY (2001)