期刊
JAPANESE JOURNAL OF OPHTHALMOLOGY
卷 53, 期 4, 页码 345-351出版社
SPRINGER JAPAN KK
DOI: 10.1007/s10384-009-0689-0
关键词
blood flow; functional intrinsic signal; metabolic responses; oximetry; perfusion maps; retinal imaging
The Retinal Function Imager (RFI; Optical Imaging, Rehovot, Israel) is a unique, noninvasive multiparameter functional imaging instrument that directly measures hemodynamic parameters such as retinal blood-flow velocity, oximetric state, and metabolic responses to photic activation. In addition, it allows capillary perfusion mapping without any contrast agent. These parameters of retinal function are degraded by retinal abnormalities. This review delineates the development of these parameters and demonstrates their clinical applicability for noninvasive detection of retinal function in several modalities. The results suggest multiple clinical applications for early diagnosis of retinal diseases and possible critical guidance of their treatment.
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