A hybrid system of carbon ink electrodes and chromatography paper on a CMOS chip and its application to enzymatic glucose sensor

Enzymatic sensors on complementary metal-oxide-semiconductor (CMOS) chips are realized using carbon ink and chromatography paper (ChrPr). Electrodes are fabricated from carbon ink on CMOS chips. The carbon ink electrodes work as well-behaving electrochemical electrodes. Enzyme electrodes are realized by covering the carbon ink electrodes on the CMOS chip with ChrPr supporting enzymes and electron mediators. Such enzyme electrodes successfully give anodic current proportional to the glucose concentration. Good linearity is observed up to 10mM glucose concentration, which is sufficient for blood glucose testing applications. (C) 2014 The Japan Society of Applied Physics