期刊
MOLECULES
卷 20, 期 12, 页码 22900-22907出版社
MDPI
DOI: 10.3390/molecules201219890
关键词
Guignardia mangiferae; meroterpenoids; structure identification; Smilax glabra; endophytic fungus
资金
- National Basic Research Program of China (973 Program) [2014CB460613]
- National Natural Science Foundation of China [81203006]
- Natural Science Foundation of Guangdong Province [2015A030313710, S2012010009773]
- Guangdong Provincial Project for Science and Technology [2015A030302060]
Four new meroterpenoids, guignardones P-S (1-4), and three known analogues (5-7) were isolated from the endophytic fungal strain Guignardia mangiferae A348. Their structures were elucidated on the basis of spectroscopic analysis and single crystal X-ray diffraction. All the isolated compounds were evaluated for their inhibitory effects on SF-268, MCF-7, and NCI-H460 human cancer cell lines. Compounds 2 and 4 exhibited weak inhibitions of cell proliferation against MCF-7 cell line.
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